The activities of bacterial pathogens in vivo

Originally published in: Philosophical transactions of the Royal Society series B. 2000..

Machine generated contents note: Introduction -- Questions about the Behaviour of Bacterial Pathogens in Vivo 3 -- H. Smith -- DNA Topology and Adaptation of Salmonella typhimurium -- to an Intracellular Environment 39 -- D. G. Marshall, C. J. Dorman, F. Bowe, C. Hale -- and G. Dougan -- New Methods for Studying Bacterial Behaviour in Vivo 61 -- The Pathogenesis of Shigella flexneri Infection: Lessons from -- in Vitro and in Vivo Studies 63 -- D. J. Philpott, J. D. Edgeworth and P. J. Sansonetti -- Detection and Analysis of Gene Expression During Infection -- by in Vivo Expression Technology 95 -- D. S. Merrell and A. Camilli -- Measurement of Bacterial Gene Expression in Vivo 127 -- I. Hautefort and J. C. D. Hinton -- Identification and Analysis of Bacterial Virulence Genes in Vivo 155 -- K. E. Unsworth and D. W. Holden -- Salmonella Interactions with Host Cells: In Vitro to in Vivo 180 -- B. B. Finlay and J. H. Brumell -- Impact of the New Methods 199 -- In Vivo Gene Expression and the Adaptive Response: From -- Pathogenesis to Vaccines and Antimicrobials 201 -- D. M. Heithoff, R. L. Sinsheimer, D. A. Low and M. J. Mahan -- Challenge of Investigating Biologically Relevant Functions -- of Virulence Factors in Bacterial Pathogens 226 -- R. Moxon and C. Tang -- Virulence Gene Regulation Inside and Outside 260 -- V. J. DiRita, N. C. Engleberg, A. Heath, A. Miller, -- J. A. Crawford and R. Yu -- Evidence for Operation in Vivo of Aspects of -- Pathogenicity Revealed by Recent Work in Vitro: -- Potential Use of New Methods 281 -- Quorum Sensing and the Population-dependent Control of Virulence 283 -- P. Williams, M. Camara, A. Hardman, S. Swift, V. J. Hope, -- K. Winzer, B. Middleton, D. I. Pritchard, B. W. Bycroft -- and D. Milton -- Type III Secretion: A Bacterial Device for Close Combat with -- Cells of Their Eukaryotic Host 317 -- G. R. Cornelis -- Evolution of Microbial Pathogens 349 -- J. Morschhauser, G. Kohler, W. Zieb-uhr, G. Blum-Oehler, -- U. Dobrindt and J. Hacker -- The Immune Responses to Bacterial Antigens Encountered in Vivo -- at Mucosal Surfaces 374 -- G. Dougan, M. Ghaem-Maghami, D. Pickard, G. Frankel, -- G. Douce, S. Clare, S. Dunstan and C. Simmons..

Includes bibliographical references (at the end of each chapter) and index..